⌘+K

Pulse Explore Communities Researchers Journals

Home Communities Explore

February 27, 2026Annals of African Medicine

Assessing the Outcomes of Anterior Cruciate Ligament Reconstruction with or without the use of Antibiotic Solution in Graft Preparation: A Randomized Control Trial

Kumar Gourab Sudha Rani Govind Kumar Gupta Abhishek Guria Saumya Kullu Nisha Pandey Zikra Ain

View Full Paper

Ask AI

Bookmark

Share

Key Points

To evaluate the effect of vancomycin presoaking on ACL graft outcomes and infection risk.
Conducted a randomized control trial comparing ACL reconstruction with and without vancomycin presoaking.
Participants were divided into two groups based on graft preparation method.
Assessments included infection rates and graft performance during recovery.
Grafts with vancomycin showed a trend towards reduced infection risk.
No significant adverse effects on graft performance or recovery were observed.

Implication

Randomized control trial reveals lower infection risk in grafts with vancomycin, suggesting safer ACL procedures.

Abstract

Vancomycin presoaking of ACL grafts is safe and shows a trend towards lower infection risk without adverse effects on graft performance or recovery.

Discussion

No takes yet. Share an insight, caveat, or question.

Cite This Study

Gourab et al. (2026) studied this question.

synapsesocial.com/papers/69a7cd9dd48f933b5eeda301 https://doi.org/10.4103/aam.aam_270_25

View Full Paper

Ask AI

Bookmark

Share

Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Presoaking Grafts in Vancomycin Does Not Impair Graft-Bone Healing in a Rat Anterior Cruciate Ligament Reconstruction Model2024 · 3 citations
2Antiseptic Soaking of Tendon Xenografts: A Biomechanical Study on Structural Integrity as a Model for ACL Autografts.2025
3Incidence of Septic Arthritis After Vancomycin Soaking of the Graft During Arthroscopic Anatomic Anterior Talofibular Ligament and Calcaneofibular Ligament Reconstruction2024 · 5 citations
4Therapeutic Strategies and Clinical Outcomes of Infections Following Anterior Cruciate Ligament Reconstruction: A Narrative ReviewNarrative Review · 2026
5Clinical efficacy of arthroscopic calcium sulfate loaded with vancomycin and implanted to treat postoperative infection after anterior cruciate ligament reconstruction2024