Central and Peripheral Neuromodulators in Functional Dyspepsia and Gastroparesis: A Symptom-Based Clinical Review.

Key Points

• To evaluate the role of central and peripheral neuromodulators in treating functional dyspepsia and gastroparesis with a focus on symptoms.
• Clinical review of existing literature on neuromodulators in FD and GP
• Evaluation of symptom-based treatment outcomes
• Assessment of current evidence quality
• Neuromodulators may improve symptoms of functional dyspepsia and gastroparesis
• A symptom-oriented approach may optimize patient outcomes
• There is a need for high-quality, subtype-specific trials to support findings