Genetic and immunologic determinants of BCG disease: from mechanism to prevention. | Synapse
March 5, 2026Open Access
Genetic and immunologic determinants of BCG disease: from mechanism to prevention.
Key Points
The study aims to explore the genetic and immunologic factors that contribute to BCG disease and how to prevent it.
Analysis of host-pathogen interactions
Review of genetic determinants
Evaluation of immunologic factors
Integration of clinical practices with molecular insights
Identified key molecular pathways related to BCG disease
Observed significant variations in host responses
Proposed integrated approaches for prevention and control
Abstract
BCG disease represents a typical case of host-pathogen interaction imbalance. Its prevention and control require an integrated approach combining molecular mechanisms and clinical practice improvements.