Patients with leprosy neuropathy can exhibit demyelinating abnormalities on EDX, particularly CB/TD in the forearm, which may misleadingly suggest an immune-mediated origin, such as multifocal CIDP. In patients from leprosy-endemic areas with a demyelinating neuropathy fulfilling electrodiagnostic criteria for CIDP, clinicians should perform a dermatological examination, repeat bacteriological and histological sampling, and consider performing a nerve biopsy if diagnostic doubt persists.
Foucard et al. (Mon,) studied this question.