Case report reveals potential dangers of hydrocortisone in patients with undiagnosed adrenal insufficiency, suggesting caution in treatment.
Careful management is required while administering hydrocortisone in patients with undiagnosed adrenal insufficiency, as it may cause osmotic demyelination syndrome or refeeding syndrome due to sudden changes in blood electrolytes.
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Sakai et al. (2026) studied this question.
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