Efficacy of micronized purified flavonoid fraction in reducing pain after anal fistula surgery: a randomized controlled trial

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Key Points

This research aims to evaluate the effectiveness of micronized purified flavonoid fraction in alleviating pain following anal fistula surgery.
Conducted as a randomized controlled trial
Included patients undergoing anal fistula surgery
Administered micronized purified flavonoid fraction post-operatively
Measured pain levels using standardized assessment tools
Patients receiving the flavonoid fraction reported significantly lower pain levels compared to the control group.
Pain reduction was noted in both acute and chronic phases post-surgery.

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Randomized controlled trial evaluates pain reduction in anal fistula surgery, suggesting efficacious intervention.

This study was registered with ClinicalTrials.gov, and its registration number is NCT06184438.

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Tsai et al. (2026) studied this question.

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