Prolonged renal dysfunction affects cisplatin dosage in locally advanced esophageal cancer, indicating treatment adjustments are necessary.
Prolonged renal dysfunction during DCF therapy for esophageal cancer reduces the relative dose intensity of cisplatin, potentially compromising survival. The pre chemotherapy serum creatinine level and urine volume on day 1 of the first cycle were identified as risk factors for prolonged renal dysfunction.
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Mohri et al. (2026) studied this question.
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