What question did this study set out to answer?

March 6, 2026npj Science of Food0 citationsOpen Access

Lycium L. flavonoids: extraction, purification, signal transduction pathways, and interactions with intestinal microbiota

TLTian LanQinghai University KZKexin ZhouQinghai University GDGuozhen Duan

Key Points

The aim is to review the extraction and biological functions of Lycium flavonoids, focusing on their health effects.
Summarizes recent advancements in extraction and purification techniques for Lycium flavonoids.
Describes biological activities and pharmacological effects of the flavonoids.
Analyzes interactions of Lycium flavonoids with gut microbiota.
Lycium flavonoids exhibit antioxidant, anti-inflammatory, and immunomodulatory effects.
Engage with signal transduction pathways like NF-κB and Keap1–Nrf2/ARE.
Act as functional prebiotics, enhancing gut microbiota and short-chain fatty acid production.

Abstract

Flavonoids are major bioactive constituents of Lycium L. with diverse pharmacological activities. This review summarizes recent advances in the extraction, characterization, and biological functions of Lycium flavonoids (LyFs). Evidence indicates that LyFs exert antioxidant, anti-inflammatory, and immunomodulatory effects via pathways such as NF-κB and Keap1–Nrf2/ARE. Notably, LyFs act as functional prebiotics by modulating gut microbiota and short-chain fatty acid production, supporting intestinal and metabolic health.

AI से पूछें

Bookmark

View Full Paper