Observational analysis shows improved liver function and lipid levels in MAFLD with mixed hyperlipidemia, suggesting potential benefits of herbal treatment.
Key Points
The study aims to explore the effects of modified Zeming Hongshan Decoction on metabolic associated fatty liver disease complicated with mixed hyperlipidemia.
Patient cases were selected from a liver clinic, adhering to MAFLD and MHLP diagnostic criteria.
62 cases in the control group received silymarin capsules alongside standard treatment; 62 in the herbal group received the decoction.
All participants underwent a 12-week treatment period.
Biomeasures such as BMI, liver function tests, lipid levels, and fibrosis indexes were compared pre- and post-treatment.
Both groups experienced significant reductions in BMI, with the herbal group showing better outcomes (P<0.05).
Improvements in liver function, lipid profiles, and fibrosis indicators were noted in both groups.
The herbal group exhibited higher efficacy in clinical symptoms and imaging results.
No adverse effects were recorded, indicating good safety of the treatment.