Comparison of Clinical Outcomes of Intravitreal 0.625% Povidone-Iodine Versus Antibiotic Injection for Postoperative Endophthalmitis

Intravitreal 0.625% PI injection was associated with fewer intravitreal injections, shorter hypopyon duration, and more favorable visual outcome-related measures, including significant visual improvement from baseline and a lower frequency of severe visual impairment, compared with intravitreal antibiotic treatment. These findings suggest that PI may be considered a safe and effective initial treatment option for postoperative endophthalmitis. Further prospective studies are needed to validate these results.