Observational study reveals the impact of microbial patterns on outcomes in patients with cholangitis, suggesting improved therapies.
-negative bacteria are the primary pathogens in acute cholangitis, and the high burden of multidrug resistance is linked to worse clinical outcomes, particularly in patients with malignant obstruction. Ongoing antibiotic stewardship and local resistance are crucial to optimize empiric therapy and improve patient outcomes.
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Hassan et al. (2025) studied this question.
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