Evaluation reveals adverse lipid profiles in patients with mild autonomous cortisol secretion, suggesting treatment implications.
The positive direction of associations between serum cortisol and lipid measures highlights that MACS carries a metabolically adverse lipid profile. Diagnosis of MACS was associated with a higher diagnosis rate of CVD and appropriately higher rates of prescription of lipid-lowering agents and a greater number of antihypertensive agents prescribed. The question remains about whether a specific directed treatment of MACS should be offered beyond risk-factor-mitigating management.
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Heald et al. (2026) studied this question.
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