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March 7, 2026npj Digital Medicine2 citationsOpen Access

Autonomous AI-assisted diabetic retinopathy screening at primary care is associated with increased presentation to eye care by at risk patients

ALAriel K. LeongJohns Hopkins UniversityRWRISA M. WOLFJohns Hopkins UniversityRCRoomasa Channa

Key Points

  • To explore the impact of AI-assisted diabetic retinopathy screening on patient access to eye care, particularly for African-Americans.
  • Analyzed data from 3745 adult diabetes patients at Johns Hopkins Medicine.
  • Utilized an autonomous AI-assisted screening program for diabetic retinopathy.
  • Applied inverse-probability-weighted regression and propensity score matching considering social determinants of health.
  • AI-assisted screening correlated with increased referrals to eye care specialists for African-American patients (p = 0.02).
  • The findings suggest that AI screening may help overcome barriers to annual screening exams in this population.
  • No strict causation can be assumed due to the exploratory nature of the study.

Abstract

Adult patients with diabetes (n = 3745) seen at Johns Hopkins Medicine primary care sites were referred to the Wilmer Eye Institute either based on a primary care provider referral or autonomous AI diagnostic result (referral was made after a positive or non-diagnostic result). An inverse-probability-weighted regression, which incorporated propensity score matching on social determinants of health and relevant clinical variables, showed that implementation of an autonomous AI-assisted diabetic screening program in a primary care clinic was associated with increased presentation to eye care specialist care by African-Americans (p = 0.02). This is significant because African-Americans have traditionally been less likely to undergo annual screening exams and more likely to present with more severe forms of diabetic retinopathy (DR). The results suggest a potential association between office-based, AI-assisted DR screening and improved downstream ophthalmic access for African-American patients. However, given that the analysis was exploratory, this association should be interpreted cautiously and further validated.

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Cite This Study

Leong et al. (2026) studied this question.

synapsesocial.com/papers/69abc0de5af8044f7a4e983fhttps://doi.org/10.1038/s41746-026-02460-5
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