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March 7, 2026SHILAP Revista de lepidopterologíaOpen Access

Design of bionic porous structure of bone scaffolds and analysis of fatigue and permeability characteristics

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Authors

LCLong ChaoQCQun ChaoFQFeng Qiuyuan

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Overview

Novel design improves fatigue and permeability in bionic bone scaffolds, suggesting promising orthopedic applications.

Key Points

  • To design a bionic porous structure for bone scaffolds and analyze their fatigue and permeability characteristics.
  • Designed scaffolds using a Voronoi diagram to control pore morphology and size.
  • Fabricated scaffolds using laser powder bed fusion with Ti-6Al-4V powders.
  • Evaluated mechanical properties via static simulation with ABAQUS and conducted fatigue tests.
  • Analyzed permeability using fluid simulation with COMSOL and in vitro testing.
  • Designed scaffolds met natural bone implant fatigue criteria by adjusting porosity and irregularity.
  • Established a mathematical relationship predicting fatigue characteristics based on porosity and irregularity.
  • The scaffolds exhibited permeability levels closer to natural bone, promoting cell proliferation.

Cite This Study

Chao et al. (2026) studied this question.

synapsesocial.com/papers/69abc1535af8044f7a4e9d4dhttps://doi.org/10.3389/fbioe.2026.1765370
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