Quasi-experimental study examines labor epidural analgesia effects on thermoregulation in expectant mothers, suggesting significant implications for maternal health.
( Br J Anaesth . 2025;135:1231-1239. doi: 10.1016/j.bja.2025.07.077) This study examined how labor epidural analgesia (LEA) affects the body’s sympathetic nervous system, particularly its role in thermoregulation. Epidural-related maternal hyperthermia (ERMH), a rise in maternal core temperature above 38 °C during labor, is a common complication linked to adverse maternal and neonatal outcomes. The study sought to determine whether LEA suppresses cholinergic and noradrenergic sympathetic function, thereby reducing the body’s ability to dissipate heat.
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Iacona et al. (2026) studied this question.
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