Breast cancer subtypes in CHEK2, ATM, and other non-BRCA germline carriers in Turkey

Key Points

• The study aims to describe the immunohistochemical subtypes in a population of breast cancer patients with non-BRCA germline variants.
• Characterized a cohort of breast cancer patients in Turkey with non-BRCA gene variants.
• Analyzed the distribution of immunohistochemical subtypes of tumors.
• Identified pathogenic or likely pathogenic variants in susceptibility genes.
• Found diverse immunohistochemical subtypes among non-BRCA variant carriers.
• Demonstrated the significance of non-BRCA germline variants in breast cancer pathology.
• Provided insights into the hereditary components of breast cancer in a Turkish population.

Abstract