( BJOG . 2025; 132:935–943. doi: 10.1111/1471-0528.18107) Cirrhosis is estimated to affect 45 per 100,000 women of childbearing potential with varying etiologies observed globally including viral hepatitis, nonalcoholic steatohepatitis, alcohol-associated liver disease, autoimmune hepatitis, and genetic disorders. Due to low fertility rates, pregnancy was historically uncommon leading to a lack of available evidence. The available evidence described a higher risk of maternal and neonatal mortality, especially for patients with esophageal varices and portal hypertension—although contemporary reports are more reassuring. This study aimed to describe the incidence of cirrhosis in pregnancy and detail maternal and neonatal outcomes.
Nana et al. (2026) studied this question.