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Meta-analysis demonstrates reduced major bleeding in patients discontinuing anticoagulation post-ablation, suggesting safety of tailored strategies.
Discontinuation of OAC after successful AF ablation markedly reduces MBE without a statistically significant increase in TE, highlighting the need for individualized post-ablation anticoagulation strategies. Randomized trials are needed to confirm the safety of tailored oral anticoagulant discontinuation in selected patients, supported by careful long-term follow-up and shared decision-making.
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Matteucci et al. (2026) studied this question.
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