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The aim was to develop a concise strategy for synthesizing indole-fused azepino and azocino derivatives.

A concise synthesis of indole-fused azepino- and azocino-indoles via acid-catalyzed 1,2-migration

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This method demonstrates efficient synthesis of indole derivatives in a modular approach, suggesting applicability for broader organic reactions.

The aim was to develop a concise strategy for synthesizing indole-fused azepino and azocino derivatives.
Utilized isatin derivatives as starting materials.
Employed allyl-metal addition and Grignard-mediated reactions.
Implemented 1,2-allyl migration under acid-catalyzed conditions.
Successfully synthesized indole-fused azepino[1,2-a]indoles and azocino[1,2-a]indoles.
Established efficiency of the modular synthesis approach.

Parui et al. (2026) studied this question.

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View Full Paper

Ask AI

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Authors

This method demonstrates efficient synthesis of indole derivatives in a modular approach, suggesting applicability for broader organic reactions.

The aim was to develop a concise strategy for synthesizing indole-fused azepino and azocino derivatives.
Utilized isatin derivatives as starting materials.
Employed allyl-metal addition and Grignard-mediated reactions.
Implemented 1,2-allyl migration under acid-catalyzed conditions.
Successfully synthesized indole-fused azepino[1,2-a]indoles and azocino[1,2-a]indoles.
Established efficiency of the modular synthesis approach.

Parui et al. (2026) studied this question.

View Full Paper

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Bookmark