The first assembled genome of Ischnoderma resinosum (Basidiomycota, edible-medicinal fungus) contributes to insights into its medicinal properties and lignocellulosic degradation potential

Ischnoderma resinosum , a species within the family Ischnodermataceae, is a nondomesticated edible fungus that possesses both wood-decaying properties and medicinal value. Despite its potential, a lack of related genomic studies has significantly limited the understanding of its evolutionary biology and practical applications. In the present study, the full genome of I. resinosum was sequenced and assembled. The final high-quality assembly comprised 34.15 Mb and contained 9418 protein-coding genes distributed across 25 contigs, with a contig N50 of 3.10 Mb. Genome analysis revealed the presence of 577 genes encoding a total of 634 carbohydrate-active enzymes. Additionally, numerous genes were implicated in the biosynthesis of terpenoids and polysaccharides. The annotated data and comparative analysis underscore that I. resinosum possesses substantial wood-decaying capacity, medicinal potential, and promising applications in food industry. • The full genome of Ischnoderma resinosum was sequenced and high-quality assembled. • Genes and gene clusters associated with degradation and metabolism were identified. • Phylogenetic analyses clarified the taxonomic classification of I. resinosum . • This study provides a valuable foundation for genetic research and applications.