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March 8, 2026Regenerative BiomaterialsOpen Access

Harnessing extracellular vesicles for ischemic stroke management

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Authors

KHKhan HaroonJYJun YuXLX. Q. Li

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Overview

This perspective demonstrates the potential of extracellular vesicles for delivering therapeutics and biomarkers in ischemic stroke, highlighting ongoing clinical trials.

Key Points

  • The research explores the role of extracellular vesicles in managing ischemic stroke and their potential as therapeutic agents.
  • Overview of current literature on extracellular vesicles and their applications in stroke management.
  • Discussion of synergistic effects with other therapeutic agents and their use as biomarkers.
  • Evaluation of ongoing clinical trials and challenges regarding clinical translation.
  • Extracellular vesicles can protect and deliver molecular cargo like proteins and DNA.
  • They show significant promise in mitigating ischemic stroke mechanisms such as neuroinflammation and apoptosis.
  • Clinical trials are exploring the efficacy of EV-based systems in therapeutic applications.

Cite This Study

Haroon et al. (2026) studied this question.

synapsesocial.com/papers/69acc5b032b0ef16a4050630https://doi.org/10.1093/rb/rbag038
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