Systematic review finds insufficient evidence of Y-90 reducing bleeding frequency in haemophilic synovitis, highlighting the need for better studies.
The conclusions of this systematic review are constrained by the absence of randomised studies and the risk of bias of the included observational studies. From an evidence-based medicine perspective, there is insufficient evidence to support Y-90 RSV reducing bleeding in haemophilic knees. This review identifies a need for at least high-quality observational studies to justify this intervention.
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Ray et al. (2026) studied this question.
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