Key result
Ketamine infusion resolves bronchospasm-induced respiratory failure and myocardial injury unmasked by a myocardial bridge.
Why the study?
Severe bronchospasm-induced physiologic stress unmasking a clinically significant myocardial bridge has rarely been reported.
Case Report (n=1)
Severe bronchospasm and resulting physiologic stress can precipitate myocardial injury by unmasking a previously asymptomatic congenital myocardial bridge.
Supports ketamine for bronchospasm failure with unmasked myocardial injury; hypothesis-generating for stress-induced unmasking of congenital bridges.
Severe bronchospasm resulting in acute respiratory failure may precipitate cardiovascular complications due to myocardial oxygen supply-demand mismatch. A myocardial bridge is a typically benign congenital coronary anomaly that may become clinically significant during periods of tachycardia and increased contractility. We report a case of acute hypoxic hypercapnic respiratory failure due to severe bronchospasm temporally associated with ceftriaxone administration, complicated by myocardial injury attributed to an incidentally identified myocardial bridge. This case highlights the diagnostic complexity of acute dyspnea and underscores the importance of recognizing myocardial bridge during physiologic stress, a phenomenon that has rarely been reported in prior case reports.
No takes yet. Share an insight, caveat, or question.
Bharat et al. (2026) conducted a case report in Severe bronchospasm and myocardial injury (n=1). Ceftriaxone-induced severe bronchospasm was evaluated. Severe bronchospasm temporally associated with ceftriaxone administration precipitated acute respiratory failure and myocardial injury, unmasking a previously undiagnosed myocardial bridge.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: