Case-control study identifies healthcare exposure as a key risk factor in hospitalized individuals, suggesting the need for localized surveillance.
In this setting, the cumulative duration of healthcare exposure (time to infection onset) was the primary driver of CRE risk. However, these risk factors are highly context-dependent and vary across different populations and facilities. Therefore, these results cannot be generalized, highlighting the need for localized surveillance and further multicenter studies to understand regional resistance dynamics.
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Zambrano-Calderero et al. (2026) studied this question.
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