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Scoping review highlights microbiome links to PTSD, suggesting need for more rigorous studies and therapies.
Current evidence supports an association between PTSD and microbiome alterations, with convergent human and preclinical findings. However, human research remains limited by small, cross-sectional designs, which preclude causal inferences. Rigorous longitudinal and interventional studies are required to establish causality and assess microbiome-targeted therapies as adjuncts in PTSD treatment.
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Berendse et al. (2026) studied this question.
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