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March 8, 20261 citationsOpen Access

A Fully Automated Design of Experiments-Based Method for Rapidly Screening Near-Optimal CO2 Injection Strategies

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DDDemis DiplasNational Technical University of AthensSFSofianos Panagiotis FotiasNational Technical University of AthensIIIsmail IsmailNational Technical University of Athens

Key Points

  • The aim is to develop a method for optimizing CO2 injection strategies using fewer simulations.
  • Utilized a Design of Experiments (DoE) framework.
  • Applied nonlinear surrogate modeling.
  • Conducted minimal high-fidelity simulations.
  • Achieved up to 97% of targeted CO2 sequestration with only 15 simulations.
  • Significantly reduced time and cost for project developers.
  • Enabled earlier risk assessment and accelerated Final Investment Decisions.

Abstract

Injection well placement and rate allocation are among the most decisive factors in determining the efficiency and bankability of CCS projects. However, optimizing these parameters is notoriously complex: even a small number of injection wells leads to a virtually infinite set of injection scenarios, while traditional optimization techniques typically require thousands of high-fidelity reservoir simulations. For project developers, this computational burden can stall critical Final Investment Decisions (FID). The approach proposed here addresses this bottleneck by using a Design of Experiments (DoE) framework combined with nonlinear surrogate modeling, which efficiently maps the relationship between injection rates and storage performance, to identify near-optimal solutions with a minimal number of simulations. We show that our method achieves up to 97% of the initially targeted CO2 sequestration with as few as 15 simulations, demonstrating a step-change reduction in time and cost. From a business standpoint, CCS operators can de-risk projects earlier, accelerate FID timelines, and evaluate multiple site configurations in parallel while minimizing computational overhead. Rather than waiting weeks or months for exhaustive optimization, decision-makers can gain timely, reliable insights that directly support capacity commitments, regulatory submissions, and ultimately revenue realization.

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Cite This Study

Diplas et al. (2026) studied this question.

synapsesocial.com/papers/69ada8cfbc08abd80d5bc181https://doi.org/10.3390/en19051361
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