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March 8, 2026NutrientsOpen Access

Small Intestinal Bacterial Overgrowth and Systemic Laboratory Parameters: A Multivariable Cross-Sectional Analysis

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Authors

MWMonika WaśkowKMKrzysztof MalinowskiMTMagdalena Tańska

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Overview

Cross-sectional analysis reveals no independent association of SIBO with vitamin D levels and hematological markers.

Key Points

  • To determine the independent clinical relevance of SIBO concerning systemic inflammatory markers and vitamin D deficiency.
  • 162 adults underwent hydrogen breath testing.
  • Serum levels of 25-hydroxyvitamin D, leukocyte count, RDW-SD, and C-reactive protein were measured.
  • Unadjusted comparisons and multivariable regression models were used for analysis, adjusting for age, sex, and BMI.
  • SIBO-positive individuals had lower vitamin D levels and higher leukocyte counts before adjustments.
  • After adjustments, SIBO status showed no independent association with vitamin D, leukocyte count, or RDW-SD.
  • BMI and age were significantly associated with leukocyte count and RDW-SD.

Cite This Study

Waśkow et al. (2026) studied this question.

synapsesocial.com/papers/69ada8dfbc08abd80d5bc3e8https://doi.org/10.3390/nu18050859
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