Why the study?
Does spironolactone affect morbidity and mortality in patients with severe heart failure?
Population
Patients with severe heart failure
Design
RCT, Randomized
Authors
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Spironolactone may reduce morbidity and mortality in severe HF; leaves open confirmation in contemporary practice.
Does spironolactone affect morbidity and mortality in patients with severe heart failure?
Pitt et al. (2000) studied this question.
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