Shexiang Tongxin dropping pills attenuate cardiac remodeling in myocardial infarction rats by inhibiting Glycolysis via ITGB2 methylation

Puntos clave

• This research aims to investigate the effects of Shexiang Tongxin pills on cardiac remodeling after a myocardial infarction by targeting glycolysis through ITGB2 methylation.
• Utilized a rat model of myocardial infarction for the intervention with Shexiang Tongxin pills.
• Assessed cardiac remodeling markers and analyzed glycolysis pathways post-treatment.
• Evaluated ITGB2 methylation patterns in cardiac tissues before and after intervention.
• Shexiang Tongxin pills significantly reduced cardiac remodeling markers compared to control.
• Inhibited glycolysis was observed with a corresponding increase in ITGB2 methylation levels in treated rats.