HAART-naïve adults with HIV demonstrated significantly higher estimated pulmonary artery systolic pressure (19.31 vs 13.60 mmHg) and a 7.5% prevalence of pulmonary hypertension compared to HIV-negative controls.
Case-Control (n=300)
Single-blind (echocardiographic evaluation performed prior to knowledge of CD4 counts)
Random selection of cases using a table of random numbers
No
Does HAART-naïve HIV infection increase estimated pulmonary artery pressure and alter right-heart echocardiographic parameters compared to HIV-negative controls?
HAART-naïve adults with HIV have significantly higher estimated pulmonary artery pressures and a 7.5% prevalence of pulmonary hypertension, indicating early right-sided cardiac involvement.
Absolute Event Rate: 19.31% vs 13.6%
p-value: p=0.001
N et al. (Thu,) conducted a case-control in HIV (HAART-naïve) (n=300). HIV infection (HAART-naïve) vs. HIV-negative controls was evaluated on Estimated pulmonary artery systolic pressure (PASP) in mmHg (p=0.001). HAART-naïve adults with HIV demonstrated significantly higher estimated pulmonary artery systolic pressure (19.31 vs 13.60 mmHg) and a 7.5% prevalence of pulmonary hypertension compared to HIV-negative controls.