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Umbrella review evaluates lifestyle interventions' impact on depression, suggesting need for further trials.
Lifestyle-based adjuvant interventions show relevant antidepressant effects, particularly supervised moderate aerobic exercise and mind-body therapies. However, heterogeneity and low methodological quality limit conclusions, highlighting the need for robust trials to define optimal dosing, durability, and effectiveness.
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Gonzalez-Garcia et al. (2026) studied this question.
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