Case report reveals Clostridium perfringens infection after ocular trauma, suggesting urgency in management.
Open globe injuries [OGIs] are ocular emergencies which can lead to visual impairment, especially when associated with infection. This case report presents a rare case of Clostridium perfringens isolated from the eye following a firecracker injury in a 38-year-old man. The patient underwent evisceration as the globe tissue was friable and could not be salvaged and promptly started on antibiotics. Anaerobic culture of a foreign body removed during surgery showed growth of C. perfringens C. perfringens , an anaerobic bacterium, is a rare but highly virulent ocular pathogen that can cause fulminant endophthalmitis, which may progress to panophthalmitis and require globe removal. • Monocular blindness is often due to ocular trauma • Globe injury is a surgical emergency, and the patient needs to be treated with surgical and medical management. • Clostridium perfringens, an uncommon ocular pathogen, is notorious for causing panophthalmitis.
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Jayagandan et al. (2026) studied this question.
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