Answers are grounded in this paper and cite their sources.
Evaluates the anti-inflammatory and anti-COVID-19 effects of ibuprofen complexes, suggesting potential therapeutic options.
This study presents the synthesis and comprehensive characterization of four novel metal-complexes formed from the reaction of copper(II), nickel(II), zinc(II), and vanadium(IV) salts with the bidentate ibuprofen Schiff base ligand (HL) in 1:1 metal-to-ligand ratio. The copper complex shows the highest antibacterial and cytotoxicity efficiency, in addition to a strong binding interactions with DNA. The in-vitro anti-inflammatory and anti-COVID-19 potencies of HL and its complexes were assessed, ranking them as: CuL > NiL > ZnL > VOL > HL.
No takes yet. Share an insight, caveat, or question.
Abdel‐Rahman et al. (2026) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: