Novel cinnamic acid derivatives enable the induction of chloroplast‐associated immunity and interaction with viral coat proteins for plant viral disease control

This study identifies B₇ as the optimal antiviral agent with superior efficacy and biosafety, defines critical structure-activity relationship principles governing cinnamic acid-based antiviral agent design, and mechanistically validates its dual-action mechanisms involving chloroplast-potentiated systemic immunity and direct TMV-CP interactions. It provides an important reference for the development of efficient and multitarget antiviral agents.