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March 6, 2026Open Access

A Meta-analysis to Identify Common Key Genes Across Ageing, Alzheimer's and Parkinson's Diseases.

Mona Chaurasiya Sai Nikhith Cholleti Gauri Prasad Vaibhav Vindal

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Key Points

The research aims to identify shared genes across ageing and neurodegenerative diseases such as Alzheimer's and Parkinson's.
Conducted a meta-analysis integrating transcriptomic data, network analysis, and miRNA studies.
Focused on identifying common molecular pathways among the diseases.
Analyzed physiological ageing alongside pathological neurodegeneration.
Identified a neurodegenerative molecular core shared across the three conditions.
Revealed several key regulatory nodes that could serve as targets for new therapies.
Demonstrated systems-level convergence in gene expression related to ageing and disease.

Implication

Meta-analysis identifies key genes linked to neurodegenerative diseases, suggesting targets for therapies.

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Cite This Study

Chaurasiya et al. (2026) studied this question.

synapsesocial.com/papers/69b2573196eeacc4fcec5d8b https://doi.org/10.1177/09727531261420619

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Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

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5Exploring Gene Expression Patterns in Alzheimer’s Disease Using a Human Microarray Data Meta-AnalysisMeta-Analysis · 2026 · 2 citations

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