This research shows enhanced hyaluronic acid in osteoarthritis treatment using a hydrogel, suggesting a new therapy approach.
Osteoarthritis In article number 2400542, Feng Zhou, Qian Chen, Bin Li, and co-workers present a hyaluronan synthase 2-encoding lentivirus-loaded dexamethasone sodium phosphate hydrogel (HAS2@DexP-Gel). The hydrogel enhances endogenous hyaluronan production, reduces synovial inflammation, and delays cartilage degeneration. This research introduces a novel combinatorial nanotherapy approach for treating osteoarthritis.
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Zhou et al. (2024) studied this question.
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