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Study establishes a higher CA72-4 reference limit, reducing false positives in health screenings, suggesting careful interpretation for older adults.
An upper reference limit of 8.5 U/mL for CA72-4 in Shenzhen healthy adults-higher than the manufacturer's value-reduces false positives in health screening. Slight age-related increases suggest cautious interpretation in the elderly. This study provides an important reference for region-specific tumor marker intervals in Shenzhen and similar populations.
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An et al. (2026) studied this question.
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