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March 12, 20260 citations

Evaluation of the Effects of Intravitreal Application of an Ozurdex Implant in Patients with Macular Edema due to Retinal Vein Occlusion.

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MLMartin LadaRŽRenata ŽeníškováZHZuzana Hradcová

Key Points

  • This research aims to evaluate the effectiveness and safety of the Ozurdex implant for treating macular edema caused by retinal vein occlusion.
  • Intravitreal application of the Ozurdex implant
  • Monitoring of best corrected visual acuity (BCVA) and central retinal thickness (CRT)
  • Assessment of intraocular pressure (IOP) during follow-up periods
  • Retreatment procedures noted between fifth and sixth month
  • Best functional and anatomical results were seen two months after treatment.
  • Decline in BCVA and increase in CRT was noted by the fourth month.
  • Retreatment was necessary for some patients between the fifth and sixth month.
  • Greatest rise in intraocular pressure occurred two months post-application, resolving by the sixth month.

Abstract

Our results indicate that Ozurdex is a safe and effective second-line treatment for macular edema (ME) due to RVO. In our group, the best functional and anatomical results were achieved two months after application. By the fourth month, a decline in BCVA and an increase in CRT were observed. Between the fifth and sixth month, retreatment was necessary in some patients. Additionally, we confirmed that the greatest rise in IOP occurred two months post-application, which resolved spontaneously by the sixth month. In four patients, IOP values above 30 mmHg were recorded during follow-up, and the intraocular pressure was managed with medication.

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Cite This Study

Lada et al. (2026) studied this question.

synapsesocial.com/papers/69b257a296eeacc4fcec6717https://doi.org/10.31348/2026/8
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