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March 12, 2026JAMA23 citations

Obesity and Cancer

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SSSherry ShenKBKristy A. BrownAGAngela K. Green

Key Points

  • To examine the relationship between obesity and cancer risk and the impact of weight loss on reducing that risk.
  • Review of current data on obesity and cancer diagnoses in the US
  • Analysis of weight loss effects on cancer risk
  • Evaluation of necessary weight loss percentage for risk reduction
  • Obesity accounts for 10% of new cancer diagnoses annually in the US
  • Significant weight loss, greater than 10%, may be necessary to reduce cancer risk

Abstract

Overweight and obesity are associated with higher rates of cancer and account for 10% of new cancer diagnoses annually in the US. Weight loss may reduce cancer risk by attenuating adverse effects of obesity, but greater than 10% weight loss may be necessary to reduce cancer risk.

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Cite This Study

Shen et al. (2026) studied this question.

synapsesocial.com/papers/69b257af96eeacc4fcec68b4https://doi.org/10.1001/jama.2026.1114
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