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A systematic review highlights the applications and challenges of quantitative susceptibility mapping in pediatric neuroimaging, suggesting future research directions.
QSM emerges as a valuable tool in pediatric neuroimaging, offering quantitative biomarkers for brain development, disease monitoring, and potential clinical translation. Despite promising results, challenges remain, including motion artifacts, lack of normative pediatric data, and methodological heterogeneity. Future research should focus on longitudinal designs, standardization of protocols, and integration with complementary imaging modalities. With further refinement, QSM has the potential to become an integral component of pediatric neuroradiological assessment.
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Pacchiano et al. (2026) studied this question.
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