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Self-controlled case series study finds limited effectiveness of stimulant treatment in preventing injuries in narcolepsy, indicating need for cautious use.
Our results indicate that overall stimulant use did not decrease the risk of fracture or head injury in patients with narcolepsy. However, methylphenidate may help prevent fractures. Clinicians should balance the safety and effectiveness of each stimulant with additional preventive strategies for injury.
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Zheng et al. (2026) studied this question.
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