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March 9, 2026

Nonextraction solution for self-injurious behavior in children with Lesch-Nyhan syndrome: a retrospective case series with up to 14 years of follow-up.

Kobi Efrat Ori Ben Joya Prof David Gozal Yaniv Ben-Atar Moti Moskovitz Joseph Shapira

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Key Points

To evaluate a nonextraction intervention for managing self-injurious behavior in children with Lesch-Nyhan syndrome.
Retrospective case series design
Follow-up period of up to 14 years
Focus on conservative intraoral techniques
Implementation by dentists trained in special care dentistry
Effective management of oral self-injurious behavior observed
Technique proved reversible compared to traditional extractions
Long-term functional outcomes maintained in experienced clinical settings

Implication

Retrospective case series finds intraoral approach effectively manages oral SIB in children, suggesting a less invasive alternative.

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Cite This Study

Efrat et al. (2026) studied this question.

synapsesocial.com/papers/69b2584996eeacc4fcec7cc0 https://doi.org/10.3290/j.qi.b6951639

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Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Dental Management of Self-Injurious Behavior in Lesch–Nyhan Disease: A Patient- and Caregiver-Reported Outcome StudyObservational Study · 2026
2Lesch-Nyhan syndrome a dental approach: case report2025
3Self-injury behaviour in children with intellectual disabilities, suspected Lesch–Nyhan syndrome: a rare genetic case2025
4Combined Anteromedial and Posteroventral Radiofrequency Pallidotomy in the Management of Severe Generalized Dystonia and Aggressivity in Lesch-Nyhan Syndrome2025
5[Clinical characteristics and treatment of two children with Lesch-Nyhan syndrome].2025

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