Cohort study shows associations between maternal acetaminophen use and child ADHD or ASDs, indicating potential biases.
The findings of this cohort study in Taiwan suggest that positive associations were observed between maternal prenatal acetaminophen prescriptions and offspring's ADHD or ASDs in the full cohort but not in the sibling-matched analyses. A substantial divergence in associations in the sibling bidirectional analyses indicates unaddressed sources of bias and prevents firm conclusions from being drawn using the sibling design.
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Lee et al. (2026) studied this question.
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