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March 12, 2026CEN Case Reports0 citationsOpen Access

A case of autosomal dominant polycystic kidney disease with multiple bilateral spontaneous retroperitoneal hemorrhages

MMMasato MizutaTSTatsuya SuwabeYOYuki Oba

Key Points

  • To explore the relationship between ADPKD and spontaneous retroperitoneal hemorrhages.
  • Case report of a 45-year-old male with ADPKD developing retroperitoneal hemorrhages.
  • Conservative management followed by renal transarterial embolization for treatment.
  • Repeated endovascular treatments over eight years due to recurrent bleeding.
  • Patient experienced multiple bilateral hemorrhages at three sites requiring repeated TAE.
  • After numerous interventions, the patient required hemodialysis to manage renal function.
  • TAE was found to be effective in controlling bleeding and preserving renal function.

Abstract

We experienced a 45-year-old male with ADPKD who developed spontaneous retroperitoneal hemorrhages with hypertension in the right subcapsular renal space without trauma. After his condition worsened with conservative management, he was treated by renal transarterial embolization (TAE). Over the next eight years, he experienced bilateral bleeding at three different sites and underwent repeated endovascular treatment with renal TAE to stop the bleeding. After the fourth occurrence, the patient underwent hemodialysis. Although renal cysts and urinary tract bleeding occur frequently in ADPKD, retroperitoneal hemorrhage is rare; however, TAE is both effective and a good way to preserve renal function.

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Cite This Study

Mizuta et al. (2026) studied this question.

synapsesocial.com/papers/69b2588496eeacc4fcec8491https://doi.org/10.1007/s13730-025-01079-x
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