Kinetics of antibodies and risk of respiratory syncytial virus infection: a longitudinal cohort in Taizhou City, eastern China

Key Points

• This research aims to analyze how antibodies change over time and their effect on the risk of RSV infection, considering age differences.
• Conducted a longitudinal cohort study in Taizhou City, eastern China.
• Monitored antibody responses after natural RSV infections across different age groups.
• Analyzed the durability and protective value of RSV PreF antibodies against infection.
• Found significant age-related differences in the durability of antibody responses.
• Identified the protective value of natural infection-elicited antibodies varies with age.
• Highlighted the need for age-specific preventive measures against RSV.