Interpenetrating gelatin/sodium alginate hydrogel with controlled PRP lysate delivery for accelerating diabetic wound healing with reduced scarring

Fairooz Nawer; Abdur Rahman; Dr Md. Ashraful Hoque; M. Tarik Arafat

doi:10.1039/d5ra09743f

January 1, 2026RSC AdvancesOpen Access

Interpenetrating gelatin/sodium alginate hydrogel with controlled PRP lysate delivery for accelerating diabetic wound healing with reduced scarring

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Key Points

The aim is to develop a hydrogel that releases growth factors to improve diabetic wound healing and minimize scars.
Developed interpenetrating network hydrogel using gelatin and sodium alginate.
Incorporated platelet-rich plasma (PRP) lysate for controlled delivery of growth factors.
Assessed the hydrogel's effectiveness in promoting tissue regeneration in diabetic wounds.
The hydrogel successfully controlled the release of PRP growth factors.
Diabetic wound healing was expedited with enhanced tissue regeneration.
Scarring was minimized compared to traditional treatments.

Implication

Natural polymer hydrogel enhances diabetic wound healing and reduces scarring via controlled growth factor delivery.

Abstract

Natural polymer based interpenetrating network hydrogel Gel/SA@PL released PL growth factors in a controlled manner to expedite diabetic wound healing with enhanced tissue regeneration and minimal scarring.

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Cite This Study

Nawer et al. (2026) studied this question.

synapsesocial.com/papers/69b258a396eeacc4fcec87d5 https://doi.org/10.1039/d5ra09743f

View Full Paper

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Interpenetrating gelatin/sodium alginate hydrogel with controlled PRP lysate delivery for accelerating diabetic wound healing with reduced scarring

Key Points

Implication

Abstract

Discussion

Cite This Study

Interpenetrating gelatin/sodium alginate hydrogel with controlled PRP lysate delivery for accelerating diabetic wound healing with reduced scarring

Key Points

Implication

Abstract

Discussion

Cite This Study

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