Pilot study shows cognitive deficits linked to pain and autonomic symptoms in hypermobile Ehlers-Danlos syndrome, indicating a need for targeted interventions.
Attention in the hEDS group was impaired compared to HC, and executive performance was dependent on body position. Individuals performed worse when standing legs-crossed. Hence, impaired proprioception as present in hEDS may, along with comorbid conditions such as pain, be a contributing factor affecting executive function.
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Müller et al. (2026) studied this question.
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