Draft genome sequence reveals cholesterol metabolizing capabilities of an Acutalibacteraceae isolate, indicating gut diversity.
We report the draft genome sequence of a family Acutalibacteraceae isolate, which is an obligate anaerobe that converts cholesterol to coprostanol. The organism was isolated from a healthy adult's fecal sample, plated on cholesterol brain agar, and incubated anaerobically, yielding distinctive star-shaped colonies. This isolate is from an unclassified genus within the Acutalibacteraceae, highlighting the unexplored diversity within the gut microbiome.
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Skolnick et al. (2026) studied this question.
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