Research evaluates glucarpidase efficacy for improving methotrexate elimination in patients, indicating significant therapeutic advancements.
Glucarpidase is an invaluable tool in the management of MTX toxicity, allowing rapid and effective reduction of MTX toxic drug levels, especially in patients with compromised renal function. To update glucarpidase administration algorithms, research is needed to evaluate its efficacy in patients with moderate MTX elevations.
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Peccatori et al. (2026) studied this question.
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