What does this research mean for the field?

Preoperative malnutrition, as evaluated by the GNRI, is independently associated with impaired postoperative health-related quality of life (HRQOL) in elderly patients undergoing spinal surgery. Novelty: ClaimNovelty.NOVEL_FINDING. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

The aim is to evaluate the relationship between preoperative nutritional status and biological age in elderly spinal surgery patients.

March 12, 2026Spine2 citations

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Can Preoperative Nutritional Status be one of the Parameters Evaluating Biological Age for Elderly Patients Undergoing Spinal Surgery? A Propensity Score–matched Analysis

YKYuki KinoshitaOsaka Metropolitan University KTKoji Tamai MOMakoto OkaJapan Atomic Energy Agency

Key Points

The aim is to evaluate the relationship between preoperative nutritional status and biological age in elderly spinal surgery patients.
Conducted a propensity score-matched analysis
Evaluated preoperative nutritional status using GNRI
Assessed postoperative health-related quality of life (HRQOL)
Preoperative malnutrition was significantly linked to reduced postoperative HRQOL.
GNRI demonstrated potential as a nutritional marker and biological age indicator.

Abstract

Preoperative malnutrition evaluated by GNRI was independently associated with impaired postoperative HRQOL in elderly patients undergoing spinal surgery. The GNRI may serve as a nutritional marker and a surrogate for biological age.

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View Full Paper

Can Preoperative Nutritional Status be one of the Parameters Evaluating Biological Age for Elderly Patients Undergoing Spinal Surgery? A Propensity Score–matched Analysis

Key Points

Abstract

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